CERTICAN

The actual benefit is substantial.

No comparison is available with the triple therapy recommended for the prophylaxis of liver transplant rejection, combining mycophenolate mofetil/low-dose tacrolimus/corticosteroids. However, in view of the lesser reduction in glomerular filtration rate demonstrated with CERTICAN/low-dose tacrolimus/corticosteroids compared to standard-dose tacrolimus/corticosteroids at 12 months and 24 months, CERTICAN in combination with low-dose tacrolimus and corticosteroids provides a minor (IAB IV) improvement in actual benefit in the prophylaxis of transplant rejection in liver allograft recipients, in comparison with standard-dose tacrolimus combined with corticosteroids.