Alternative(s) to perfusion scintigraphy in case of suspected non-massive pulmonary embolism in pregnant women in the event of a complete shortage of technetium-99m - INAHTA Brief

Due to several periods of worldwide supply shortage of technetium-99m (Tc-99m), a radioactive element needed to perform lung perfusion scintigraphy in case of suspected non-massive pulmonary embolism (PE), the Ministry of Health (DGS) asked HAS to determine if, in the event of complete shortage of this isotope, one (or more) test(s) could replace it without risk to the pregnant woman.

Currently, Tc-99m lung perfusion scintigraphy is the medical imaging test of choice in pregnant women initially without signs of shock or hypotension (especially if the triage chest x-ray is normal) when this test is readily accessible for the clinician. Offering good diagnostic performances, lung perfusion scintigraphy is not very radiating for the mother and foetus.

The objective of this assessment was not to question the current standard strategy in this situation or to establish good practice guidelines