Clinical usefulness of vitamin B1 testing - INAHTA Brief

The National Health Insurance asked the HAS to determine whether reimbursement of vitamin B1 testing, currently only applying to public hospitals, should be extended to other care structures or not. This assessment is therefore carried out in the context of controlling medical expenditure.

Two main subjects were selected for assessing the clinical usefulness of vitamin B1 testing:

• Subject 1: Is there a consensual reference interval for defining vitamin B1 deficiency? Is having a vitamin B1 result lower than the reference interval an indicator of an increase in the risk of deficiency-related complications?
• Subject 2: Where a reference interval exists, does vitamin B1 supplementation guided by the test result improve the benefit/risk ratio compared to supplementation initiated without this data?