Reason for request

Indication extension

Summary of opinion

Unfavourable opinion for reimbursement in “the treatment of adult patients with NSCLC whose tumours have an activating HER2 (ERBB2) mutation and who require systemic therapy following platinum-based chemotherapy with or without immunotherapy”.


Clinical Benefit

Insufficient

The Committee deems that the clinical benefit of ENHERTU (trastuzumab deruxtecan) is insufficient to justify public funding cover in the MA indication in view of the available alternatives.


Clinical Added Value

Not applicable

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Évaluation des médicaments